The TendoSedam® complex, a proprietary formula of 9 plant extracts, is a groundbreaking combination of active ingredients to support tendons, ligaments and connective tissue. In this article, we will examine this complex in depth, explain its ingredients in detail and highlight its diverse applications for connective tissue and injuries.
What is the TendoSedam® Complex?
The TendoSedam® complex is a special formulation consisting of 9 carefully selected plant extracts. This unique combination was developed to support and optimize the structure and function of tendons, ligaments and connective tissue.
What is the TendoSedam® complex used for?
The TendoSedam® complex is used to promote the health and regeneration of tendons, ligaments and connective tissue. It is used both preventively to optimize the stability and elasticity of the tissue and to support the healing of injuries and microlesions.
How does the TendoSedam® complex work?
The TendoSedam® complex works in several ways to improve the structure and function of the connective tissue:
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Promotes collagen formation: The plant extracts contained promote the formation of the body's own collagen, which is crucial for the structure and elasticity of tendons, ligaments and connective tissue. This helps to improve the collagen structure and regenerate the tissue.
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Anti-inflammatory and wound-healing effect: The selected plant extracts have an anti-inflammatory effect and support wound healing in microlesions within the collagen structure. This promotes faster tissue regeneration and reduces the risk of inflammation.
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Reduction of swelling and edema: The ingredients of the TendoSedam® complex improve microcirculation and can thus reduce swelling and edema in the tissue. This supports faster recovery and reduces discomfort after injuries.
Overall, the synergistic effect of the 9 plant extracts in the TendoSedam® complex enables a wide range of support for the structure and function of tendons, ligaments and connective tissue. This proprietary formula is a valuable supplement for anyone who wants to optimize their health and performance in the area of connective tissue.
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Effect of the individual plant extracts:
Sweet clover
• active ingredient coumarin
• strong anti-inflammatory effect
• improves microcirculation in the tissue and reduces the formation of edema
• promotes wound healing
Pleşca Manea, L., et al. (2002). "Effects of Melilotus officinalis on acute inflammation." Phytotherapy Research 16(4): 316 319.
Chorepsima , S., et al. (2013). "Melilotus: Contribution to wound healing in the diabetic foot." Journal of Herbal Medicine 3(3): 81 86.
birch
• active ingredients: triterpenes e.g. betulin
• strong anti-inflammatory effect
• reduces proliferation of inflammatory lymphocytes
• promotes wound healing
Gründermann, C., et al. (2011). "An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes." Journal of Ethnopharmacology 136(3): 444 451.
Fan, T. and R. Daniels (2021). "Preparation and Characterization of Electrospun Polylactic Acid (PLA) Fiber Loaded with Birch Bark Triterpene Extract for Wound Dressing." AAPS PharmSciTech 22(6): 205.
Ebeling, S., et al. (2014). "From a Traditional Medicinal Plant to a Rational Drug:
Understanding the Clinically Proven Wound Healing Efficacy of Birch Bark Extract." PLOS ONE 9(1): e86147.
Horsetail
• active ingredients: silicon, flavonoids (e.g. quercetin
• promotes the synthesis of collagen
• Stabilization and mineralization of collagen and connective tissue
• increases efficiency and the development of muscle mass
• promotes repair of muscle tendons and micro-traumas
Sadowska, A. and F. Świderski (2020). "Sources, Bioavailability, and Safety of Silicon Derive from Foods and Other Sources Added for Nutritional Purposes in Food Supplements and Functional Foods." Applied Sciences 10(18): 6255.
Jugdaohsingh, R. (2007). "Silicon and bone health." J Nutr Health Aging 11(2): 99 110. Molinari, ML (2018). "Performance Improvement in Human and Animal Athletes." Journal of Nutritional Ecology and Food Research 5(1): 65 70.
buckeye
• Active ingredient: Aescin
• vasoconstricting effect
• reduces edema
• anti-inflammatory effect
• Use for swollen legs or arms
• Phytotherapy of chronic venous insufficiency
Sirtori, C.R. (2001). Aescin: pharmacology, pharmacokinetics and therapeutic profile." Pharmacological Research 44(3): 183 193.
licorice
• Active ingredients: Triterpenes (glycyrrhizic acid)
• strong anti-inflammatory effect
• Glycyrrhizic acid can reduce inflammatory processes in ligaments
• Glycyrrhizic acid can completely prevent the development of Achilles tendinopathy
inhibit
Zhang, C., et al. (2020). "Extracellular HMGB 1 activates inflammatory signaling in tendon cells and tissues." Therapeutic Advances in Chronic Disease 11: 2040622320956429.
Zhao, G., et al. (2019). "HMGB1 mediates the development of tendinopathy due to mechanical overloading." PLOS ONE 14(9): e0222369.
Pastorino, G., et al. (2018). " Liquorice (Glycyrrhiza glabra): A phytochemical and
pharmacological review." Phytotherapy Research 32(12): 2323 2339.
sage
• active ingredients: flavonoids and terpenes camphor, cineole, rosmarinic acid
• Pain-relieving effects & anti-inflammatory effects
Ghorbani , A. and M. Esmaeilizadeh (2017). "Pharmacological properties of Salvia officinalis and its components." Journal of Traditional and Complementary Medicine 7(4): 433 440.
Small-leaved linden
• active ingredients: procyanidins
• strong anti-inflammatory effects
• Reduction of proinflammatory cytokines
• Pain-relieving effect
Czerwińska, ME, et al. (2018). "The influence of procyanidins isolated from small leaved lime flowers Tilia cordata Mill.) on human neutrophils." Fitoterapia 127: 115 122.
Fawzy, G., et al. (2018). "Anti-inflammatory, Antinociceptive and Nephroprotective activities of Tilia cordata and Isolation of Bioactive
Compounds." J. Mat. Environ. Sci 9: 1908 1914
Swamp Bloodeye
• active ingredients: tannins, triterpenes
• anti-inflammatory and analgesic effect
• Regenerating effect on the connective tissue, increases structure and
elasticity
• traditionally used for rheumatic complaints and wound healing
Tomczyk , M. and KP Latté (2009). "Potentilla A review of its phytochemical and
pharmacological profile." Journal of Ethnopharmacology 122(2): 184 204.
Popov, SV, et al. (2005). "
Antiinflammatory activity of the pectic polysaccharide from
Comarum palustre." Fitoterapia 76(3): 281 287.
Comfrey
• active ingredients: allantoin, rosmarinic acid
• anti-inflammatory effect
• pain-relieving effect
• promotes tissue regeneration and wound healing
• applied externally, it is effective for bruises, sprains and
Sprains
Staiger, C. (2012). "Comfrey: A Clinical Overview." Phytotherapy Research 26(10): 1441 1448.
Vostinaru, O., et al. (2018). "Anti inflammatory and antinociceptive effect of Symphytum officinale root." Rome Biotechnol Lett 23(6): 14160 14167.
Frost, R., et al. (2014). "The external use of comfrey: A practitioner survey." Complementary Therapies in Clinical Practice 20(4): 347 355.
