Intensive regeneration through activation of autophagy.
Under optimal conditions, the body can have an enormous regenerative capacity. However, as we age, the body may no longer produce sufficient amounts of some vital substances and the body can therefore no longer effectively initiate important regenerative processes such as autophagy. In this process, deposits in the cells, such as byproducts and breakdown products of natural metabolism or faulty proteins, can be enclosed in small vesicles in order to break them down into their components. In this way, autophagy can help to remove harmful deposits in the cells and support the cleansing of the cells.
Many aging processes can also become visible externally through the skin, which is the largest and most diverse organ in the human body. The skin and connective tissue can lose elasticity and moisture due to a possible lack of hyaluronic acid, collagen or elastin, and skin aging can begin as a result.
The lack of vital substances can be the reason why regeneration processes in the body can no longer run as effectively. According to current scientific findings, the cells are burdened with deposits due to reduced autophagy activity in old age. ⁴ . As a result, the cells lose their functionality, which can lead to age-related diseases such as Alzheimer's, joint problems or cardiovascular diseases ⁴ ' ⁵ .
Supplementing the body's own substances , which are no longer produced sufficiently with age, can promote healthy aging and enable vitality and mobility even in old age!
Chaga medicinal mushroom extract
Over 200 different biologically active substances can be detected in the Chaga medicinal mushroom extract , which can have different positive effects on health. The Chaga medicinal mushroom is traditionally used in various cultures such as China, Korea, Japan and the Scandinavian countries to promote health. The traditional use of Chaga for inflammation in the body and to strengthen the immune system is based on many years of experience. The mushroom is often prepared as a tea and can help reduce inflammation and strengthen the immune system. Its natural ingredients, which include the very highly bioactive polysaccharides (multiple sugars), can have anti-inflammatory and immunomodulatory effects that can help promote health. Numerous new studies suggest that Chaga can have strong anti-inflammatory and antioxidant effects , can provide helpful support for diabetes and can also have a stimulating effect on the immune system. ¹³ ' ¹⁴ .
Our highly concentrated Chaga medicinal mushroom extract is produced carefully and contains the numerous vital substances in the highest concentration . We work with an innovative extraction method using vegetable glycerin as an extraction agent and can therefore extract the valuable ingredients from the Chaga medicinal mushroom without alcohol.
Hyaluron and collagen peptides
Hyaluronic acid is a natural substance found in the skin, joints and other tissues. Hyaluron has the ability to bind large amounts of water ¹⁵ and can therefore play a crucial role in maintaining the moisture and elasticity of the skin. However, studies have shown that as we age, the body's production of hyaluronic acid can decrease, which can lead to dryness, wrinkles and a loss of skin firmness.
Collagen is the most common structural protein in the human body and forms the basic framework for skin, bones, tendons and cartilage ² . It gives the skin firmness and elasticity. When hyaluronic acid and collagen work together, a harmonious combination can be created that can moisturize the skin from within while improving its structure and elasticity.
This synergy can have positive effects on the body , not only on the external appearance but also on the health of the joints. Hyaluronic acid can influence the viscosity of the synovial fluid and help lubricate the joints ¹⁵ , while collagen can support the structure of cartilage tissue ² ' ¹⁶ . In combination, they can provide flexibility and mobility even in old age. Another important aspect is the role of these two substances in supporting collagen production in the body. Hyaluronic acid can act as a catalyst for collagen formation, which in turn can promote skin regeneration and the stability of connective tissue. Overall, research shows that the combination of hyaluronic acid and collagen is a promising strategy for healthy aging, not only providing aesthetic benefits but also being able to support the underlying structures of the body.
Scientific studies
¹ Saranraj, P. and M. Naidu (2013). "Hyaluronic acid production and its applications—a review." Int J Pharm Biol Arch 4(5): 853-859.
² David, MR and L. Jennifer (2021). "Skin collagen through the lifestages: importance for skin health and beauty." Plastic and Aesthetic Research 8:2.
³ Madeo, F., et al. (2020). "Nutritional Aspects" Annual Review of Nutrition 40(1): 135-159.
⁴ Morselli, E., et al. (2009). "Autophagy mediates pharmacological lifespan extension by resveratrol." Aging 1(12): 961-970.
⁵ Madeo, F., et al. (2019). "a physiological autophagy inducer acting as an anti-aging vitamin in humans?" Autophagy 15(1): 165-168.
⁶ Fîlfan, M., et al. (2017). "Autophagy in aging and disease." Rome J Morphol Embryol 58(1): 27-31.
⁷ Matsumoto, M. (2015). Polyamines and longevity in mammals. Polyamines, Springer: 257-266.
⁸ Morselli, E., et al. (2011). "Resveratrol induces autophagy by distinct pathways converging on the acetylproteome." The Journal of cell biology 192: 615-629.
⁹ Yang, X., et al. (2020). "inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans." Aging 12(17): 16852.
¹² Abdellatif, M., et al. (2018). "Autophagy in Cardiovascular Aging." Circulation Research 123(7): 803-824.
¹³ Ern, PTY, et al. "Therapeutic properties of Inonotus obliquus (Chaga mushroom): a review." Mycology: 1-18.
¹⁴ Kim, YO, et al. (2005). "Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus." Life Sciences 77(19): 2438-2456.
¹⁵ Gupta, RC, et al. (2019). "Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory." Frontiers in Veterinary Science 6.
¹⁶ T, W., et al. (2017). "Efficacy of Oral Collagen in Joint Pain - Osteoarthritis and Rheumatoid Arthritis." Journal of Arthritis 06(02).